RE: Leveraging Biospecimen Resources for Discovery or Validation of Markers for Early Cancer Detection
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منابع مشابه
RE: Leveraging Biospecimen Resources for Discovery or Validation of Markers for Early Cancer Detection.
Validation of early detection cancer biomarkers has proven to be disappointing when initial promising claims have often not been reproducible in diagnostic samples or did not extend to prediagnostic samples. The previously reported lack of rigorous internal validity (systematic differences between compared groups) and external validity (lack of generalizability beyond compared groups) may be ef...
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ژورنال
عنوان ژورنال: Journal of the National Cancer Institute
سال: 2015
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djv215